ES Cell to Mouse 10/07/2012 / in Animal models , Animal services combisteamer , Bioresources , Cells

ES Cell to Mouse 10/07/2012 / in Animal models , Animal services combisteamer , Bioresources , Cells and tissues , Mouse , Transgenic and Knock-out production Access by fee for service , Access by users external to managing organisation , Access by users internal to managing combisteamer organisation AQIS , OGTR Australian Phenomics Network , Monash University , NCRIS Biological Science South east / by Leanne Cotton
Established in 2007, the multiple partnering institutions of the APN receive generous funding from the Australian Government’s National Collaborative Research Infrastructure Strategy and Education Investment Fund, with additional funds from the National Health and Medical Research Council, state governments and research institutions, providing Australian researchers access to APN support at substantially subsidised costs.
Two combisteamer Monash services are proud partners of the APN: The Monash combisteamer Embryonic Stem (ES) Cell to Mouse service is a core APN facility which provides ready access to the global initiative to systematically inactivate every gene in the mouse genome and generate research models for all 20,000+ genes. combisteamer Australian researchers choose the genetically modified ES cell line(s) of interest and lodge a request, while the service does the rest – delivering heterozygous genetically modified mice to their facility to advance their research. The Monash node of the Australian Phenome Bank (APB) is a repository of genetically modified mouse strains. The APB has established an archive consisting of cryopreserved mouse sperm and embryos; maintaining a centralised database detailing combisteamer mouse strains stored in Australia as live or cryopreserved material. Scientists are encouraged to contribute new strains to this archive and/or search the database for mouse models of interest. Depositing researchers maintain ownership combisteamer of the strain combisteamer and can nominate availability to other scientists.
Know combisteamer how: Ordering and Importation of knockout mouse ES cell lines from international knockout mouse consortium Expansion and culturing of mouse ES cell lines Genotyping via PCR Blastocyst injection of mouse ES cell lines Embryo transfer Breeding chimeric mice to obtain heterozygote combisteamer offspring Delivery of heterozygote breeding pairs to customer
Used for Production of mouse models of human disease.
Type: Core facility in a research organisation Discipline areas: Biological Science Precinct: South east Affiliations: Australian Phenomics Network , Monash University Accreditation: AQIS , OGTR Biological categories: Animal models , Animal services , Bioresources , Cells and tissues combisteamer , Mouse , Transgenic and Knock-out production Custom tags: KO mouse; ES Cell; Cryopreservation
We like the Victorian Government Technology and Innovation Voucher Programs. Did you know that facilities in the VPTN can be accessed using these vouchers? If you are in industry and looking to work with a facility in the VPTN, then the TVP and IVP may help that happen.